The present research collaboration aims to study platelet cross-talk with lymphocytes and BM-PCs during atherogenesis, and to investigate P-selectin- and

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Catalog Number BBE6 Catalog Number SBBE6 Catalog Number PBBE6 For the quantitative determination of human P-Selectin (P-Selectin) in cell culture supernates, serum, and plasma. Sidofältlista: ordna och bläddra begrepp efter kriterier. Lista begrepp alfabetiskt; Alfabetisk; Lista begrepp enligt hierarkin; Hierarki An adhesion receptor molecule for white blood cells that functions during inflammation and tissue repair. Binding with P-selectin glycoprotein ligand 1, it controls the flow of white blood cells and their adhesion to blood vessel walls. It is viewed as a key factor in thrombosis. P-selectin plasma from blood samples taken from the subjects of the study was analyzed and compared. A set of P-selectin was purchased from Randox Laboratories Limited (UK).

25 These two forms of soluble P-selectin are elevated in humans in association with atherosclerosis and thrombosis and are predictive of future adverse cardiovascular events, including The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating interactions between blood cells and the endothelium, and also because of the possible use of the soluble form as a plasma predictor of adverse cardiovascular events. Although present on the external cell surfa … P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha. P-selectin is a cell adhesion molecule of platelets and endothelial cells stored in secretory granules and rapidly expressed on the plasma membrane on activation.10-13 After expression on the cell surface both endothelial and platelet P-selectin mediate leukocyte adhesion.14 Whereas endothelial P-selectin has clearly been shown to be involved in leukocyte and platelet rolling,15,16 the role of P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets.

P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets.

P-Selectin P-selektin Engelsk definition. Cell adhesion molecule and CD antigen that mediates the adhesion of neutrophils and monocytes to activated platelets and endothelial cells. 2011-08-17 · P-selectin expression is involved in the pathophysiology of biologically active arterial thrombus and endothelial activation after a transient ischemic event. Fucoidan is a polysaccharidic ligand of P-selectin, with a nanomolar affinity.

P-selectin. P-selektin lagras i trombocyternas α-granula. Vid aktivering flyttas molekylen till cellytan. Där fungerar proteinet som receptor för neutrofila granulocyter.

2021-03-26 P‑Selectin/CD62P in Mouse Liver. P-Selectin/CD62P was detected in perfusion fixed frozen sections of mouse liver using Goat Anti-Mouse/Rat P-Selectin/CD62P Antigen Affinity-purified Polyclonal Antibody (Catalog # AF737) at 5 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). P-selectin was constitutively expressed at low levels on the surface of passage 1 HUVEC. Exogenous administration of thrombin resulted in a marked and rapid, dose-dependent increase in the surface P-selectin expression within 10 min of stimulation (Fig.

re , än Hertigens voro , den tid han var i dess våld ; v ) Fant Observ . Select . in Hist , Svecan , P . V , p . än Hertigens voro , den tid han var i dess 1 våld ; och kunde sådant icke medgifvas , begär Konungen.
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Regnaud , P. , De primigenia vocis Kshatriyari atque de regiis insignibus P. 1. Inscriptiones Phoenicias continens. T. 1: 1–3 (text & pl.).

[5] P-selectin functions as a cell adhesion molecule (CAM) on the surfaces of activated endothelial cells, which line the inner surface of blood vessels, and activated platelets . P-Selectin (CD62P), previously termed PADGEM or GMP-140, is a single chain glycoprotein of 140 kDa expressed in platelets and endothelial cells. In platelets, P-selectin is stored in α granules, whereas in endothelial cells it is found in Weibel–Palade bodies. P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling.
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2020-03-01

Meaning of p-selectin. What does p-selectin mean?

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May 28, 2020 Although P-selectin expression is considered limited to platelets and endothelial cells (4), Yen et al. (12) surprisingly demonstrated the

P-selectin can be secreted into the circulation as a component of EC and platelet-derived microparticles (MP) or, in small quantities, as a free, alternatively spliced version lacking a transmembrane domain. 25 These two forms of soluble P-selectin are elevated in humans in association with atherosclerosis and thrombosis and are predictive of future adverse cardiovascular events, including The adhesion molecule P-selectin (CD62P) is of interest because of its role in modulating interactions between blood cells and the endothelium, and also because of the possible use of the soluble form as a plasma predictor of adverse cardiovascular events. Although present on the external cell surfa … P-selectin (Selectin P, GMP-140, LECAM3, CD62 antigen-like family member) is a 140 kDa type 1 transmembrane glycoprotein, and is one of the most commonly studied proteins that regulate cell rolling. P-selectin is stored in the Weibel-Palade bodies of endothelial cells, as well as in a-granules of platelets. P-Selectin, also known as CD62P, GMP-140, PADGEM, and LECAM-3, is a transmembrane adhesion protein that is upregulated on activated platelets and vascular endothelial cells. It binds to hematopoietic cell PSGL-1/CD162 with highly clustered O-linked sialyl Lewis-x (sLex ) tetrasaccharides and sulfated tyrosine, as well as to heparin sulfate, Versican, and CD42b/GPIb alpha.

Selectin P ligand, also known as SELPLG or CD162 (cluster of differentiation 162 ), is a human gene. SELPLG codes for PSGL-1, the high affinity

Elevated P-selectin was associated with 1.7-fold increase in the risk of venous thrombosis. Materials and Methods. To confirm the association, a total of 91 subjects who received primary total hip arthroplasty using lateral approach performed by one skilled orthopedic surgeon were studied. 2019-07-12 · P-Selectin Antibody (CTB201) is a monoclonal anti-CD62 antibody that detects m, r, and h P-Selectin by WB, IP, IF, IHC(P) and FCM. Cited in 38 publications Search results for p-selectin at Sigma-Aldrich. Summary: This gene encodes a glycoprotein that functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes.